Cargando…

Notch Activation Differentially Regulates Renal Progenitors Proliferation and Differentiation Toward the Podocyte Lineage in Glomerular Disorders

Glomerular diseases account for 90% of end-stage kidney disease. Podocyte loss is a common determining factor for the progression toward glomerulosclerosis. Mature podocytes cannot proliferate, but recent evidence suggests that they can be replaced by renal progenitors localized within the Bowman�...

Descripción completa

Detalles Bibliográficos
Autores principales: Lasagni, Laura, Ballerini, Lara, Angelotti, Maria Lucia, Parente, Eliana, Sagrinati, Costanza, Mazzinghi, Benedetta, Peired, Anna, Ronconi, Elisa, Becherucci, Francesca, Bani, Daniele, Gacci, Mauro, Carini, Marco, Lazzeri, Elena, Romagnani, Paola
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996085/
https://www.ncbi.nlm.nih.gov/pubmed/20680961
http://dx.doi.org/10.1002/stem.492