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Anti-Malaria Drug Mefloquine Induces Motor Learning Deficits in Humans

Mefloquine (a marketed anti-malaria drug) prophylaxis has a high risk of causing adverse events. Interestingly, animal studies have shown that mefloquine imposes a major deficit in motor learning skills by affecting the connexin 36 gap junctions of the inferior olive. We were therefore interested in...

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Detalles Bibliográficos
Autores principales: van Essen, Thomas A., van der Giessen, Ruben S., Koekkoek, Sebastiaan K. E., VanderWerf, Frans, Zeeuw, Chris I. De, van Genderen, Perry J. J., Overbosch, David, de Jeu, Marcel T. G.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996171/
https://www.ncbi.nlm.nih.gov/pubmed/21151372
http://dx.doi.org/10.3389/fnins.2010.00191