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A Mutant of SWAP-70, a Phosphatidylinositoltrisphosphate Binding Protein, Transforms Mouse Embryo Fibroblasts, Which Is Inhibited by Sanguinarine

SWAP-70, a phosphatidylinositol trisphosphate (PtdIns(3,4,5)P(3)) binding protein, has been suggested to be involved in transformation of mouse embryo fibroblasts (MEFs) as well as membrane ruffling after growth factor stimulation of the cells. A mutant, SWAP-70-374, was found to be able to bind to...

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Detalles Bibliográficos
Autores principales: Fukui, Yasuhisa, Ihara, Sayoko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996291/
https://www.ncbi.nlm.nih.gov/pubmed/21152038
http://dx.doi.org/10.1371/journal.pone.0014180