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A Mutant of SWAP-70, a Phosphatidylinositoltrisphosphate Binding Protein, Transforms Mouse Embryo Fibroblasts, Which Is Inhibited by Sanguinarine
SWAP-70, a phosphatidylinositol trisphosphate (PtdIns(3,4,5)P(3)) binding protein, has been suggested to be involved in transformation of mouse embryo fibroblasts (MEFs) as well as membrane ruffling after growth factor stimulation of the cells. A mutant, SWAP-70-374, was found to be able to bind to...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996291/ https://www.ncbi.nlm.nih.gov/pubmed/21152038 http://dx.doi.org/10.1371/journal.pone.0014180 |