ATF3 Plays a Key Role in Kdo(2)-Lipid A-Induced TLR4-Dependent Gene Expression via NF-κB Activation

BACKGROUND: Activating transcription factor 3 (ATF3) is a negative regulator of proinflammatory cytokine expression in macrophages, and ATF3 deficient mice are more susceptible to endotoxic shock. This study addresses the role of ATF3 in the Kdo(2)-Lipid A-induced Toll-like receptor 4 (TLR4) signali...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Young, Shin, Hye Young, Kim, Joo-Young, Kim, Dong-Gun, Choi, Yong-Min, Kwon, Hyuk-Kwon, Rhee, Dong-Kwon, Kim, You-Sun, Choi, Sangdun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996292/
https://www.ncbi.nlm.nih.gov/pubmed/21152039
http://dx.doi.org/10.1371/journal.pone.0014181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996292/
https://www.ncbi.nlm.nih.gov/pubmed/21152039
http://dx.doi.org/10.1371/journal.pone.0014181

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