Cargando…

ATF3 Plays a Key Role in Kdo(2)-Lipid A-Induced TLR4-Dependent Gene Expression via NF-κB Activation

BACKGROUND: Activating transcription factor 3 (ATF3) is a negative regulator of proinflammatory cytokine expression in macrophages, and ATF3 deficient mice are more susceptible to endotoxic shock. This study addresses the role of ATF3 in the Kdo(2)-Lipid A-induced Toll-like receptor 4 (TLR4) signali...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Eun-Young, Shin, Hye Young, Kim, Joo-Young, Kim, Dong-Gun, Choi, Yong-Min, Kwon, Hyuk-Kwon, Rhee, Dong-Kwon, Kim, You-Sun, Choi, Sangdun
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996292/ https://www.ncbi.nlm.nih.gov/pubmed/21152039 http://dx.doi.org/10.1371/journal.pone.0014181

Ejemplares similares

Doxorubicin Induces Cytotoxicity through Upregulation of pERK–Dependent ATF3
por: Park, Eun-Jung, et al.
Publicado: (2012)

Activating transcription factor 3 represses inflammatory responses by binding to the p65 subunit of NF-κB
por: Kwon, Ji-Woong, et al.
Publicado: (2015)

TLR4 Mediates Pneumolysin-Induced ATF3 Expression through the JNK/p38 Pathway in Streptococcus pneumoniae-Infected RAW 264.7 Cells
por: Nguyen, Cuong Thach, et al.
Publicado: (2015)

USP8 regulates liver cancer progression via the inhibition of TRAF6-mediated signal for NF-κB activation and autophagy induction by TLR4
por: Kim, Mi-Jeong, et al.
Publicado: (2021)

Kdo Hydrolase Is Required for Francisella tularensis Virulence and Evasion of TLR2-Mediated Innate Immunity
por: Okan, Nihal A., et al.
Publicado: (2013)

Nargenicin A1 attenuates lipopolysaccharide-induced inflammatory and oxidative response by blocking the NF-κB signaling pathway
por: Kwon, Da Hye, et al.
Publicado: (2021)

REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-κB activation
por: Lee, Dong-Keon, et al.
Publicado: (2022)

ATF3 Stimulates IL-17A by Regulating Intracellular Ca(2+)/ROS-Dependent IL-1β Activation During Streptococcus pneumoniae Infection
por: Lee, Seungyeop, et al.
Publicado: (2018)

A peptide derived from the core β-sheet region of TIRAP decoys TLR4 and reduces inflammatory and autoimmune symptoms in murine models
por: Achek, Asma, et al.
Publicado: (2020)

Roles of TLR7 in Activation of NF-κB Signaling of Keratinocytes by Imiquimod
por: Li, Zheng Jun, et al.
Publicado: (2013)

The Role of NF-κB in Chronic Rhinosinusitis With Nasal Polyps
por: Jung, Hahn Jin, et al.
Publicado: (2019)

Carbon monoxide prevents TNF-α-induced eNOS downregulation by inhibiting NF-κB-responsive miR-155-5p biogenesis
por: Choi, Seunghwan, et al.
Publicado: (2017)

Salicortin suppresses lipopolysaccharide-stimulated inflammatory responses via blockade of NF-κB and JNK activation in RAW 264.7 macrophages
por: Kwon, Dong-Joo, et al.
Publicado: (2014)

NF-κB-responsive miR-155 induces functional impairment of vascular smooth muscle cells by downregulating soluble guanylyl cyclase
por: Park, Minsik, et al.
Publicado: (2019)

Isorhamnetin alleviates lipopolysaccharide-induced inflammatory responses in BV2 microglia by inactivating NF-κB, blocking the TLR4 pathway and reducing ROS generation
por: Kim, Shin Young, et al.
Publicado: (2019)

FFAR2 antagonizes TLR2- and TLR3-induced lung cancer progression via the inhibition of AMPK-TAK1 signaling axis for the activation of NF-κB
por: Kim, Mi-Jeong, et al.
Publicado: (2023)

Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis
por: Wee, Jee Hye, et al.
Publicado: (2017)

Korean Red Ginseng Up-regulates C21-Steroid Hormone Metabolism via Cyp11a1 Gene in Senescent Rat Testes
por: Kim, In-Hye, et al.
Publicado: (2011)

Platelet-activating Factor–mediated NF-κB Dependency of a Late Anaphylactic Reaction
por: Choi, Il-Whan, et al.
Publicado: (2003)

Korean Red ginseng prevents endothelial senescence by downregulating the HO-1/NF-κB/miRNA-155-5p/eNOS pathway
por: Kim, Tae-Hoon, et al.
Publicado: (2021)

Schisandrin A suppresses lipopolysaccharide-induced inflammation and oxidative stress in RAW 264.7 macrophages by suppressing the NF-κB, MAPKs and PI3K/Akt pathways and activating Nrf2/HO-1 signaling
por: Kwon, Da Hye, et al.
Publicado: (2018)

β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4
por: Kim, Ji Young, et al.
Publicado: (2023)

Impact of KDO in biological activity of Re-LPS
por: Prokhorenko, I, et al.
Publicado: (2014)

NF-κB-dependent miR-31/155 biogenesis is essential for TNF-α-induced impairment of endothelial progenitor cell function
por: Kim, Ji-Hee, et al.
Publicado: (2020)

Quercus acuta Thunb. (Fagaceae) and Its Component, Isoquercitrin, Inhibit HSV-1 Replication by Suppressing Virus-Induced ROS Production and NF-κB Activation
por: Kim, Buyun, et al.
Publicado: (2021)

Structural and functional analysis of cell adhesion and nuclear envelope nano-topography in cell death
por: Kwon, Hyuk-Kwon, et al.
Publicado: (2015)

Schisandrae Fructus ethanol extract attenuates particulate matter 2.5-induced inflammatory and oxidative responses by blocking the activation of the ROS-dependent NF-κB signaling pathway
por: Lee, Hyesook, et al.
Publicado: (2021)

JQ1, a BET inhibitor, controls TLR4-induced IL-10 production in regulatory B cells by BRD4-NF-κB axis
por: Lee, Min Bum, et al.
Publicado: (2017)

Korean Red Ginseng extract reduces hypoxia-induced epithelial-mesenchymal transition by repressing NF-κB and ERK1/2 pathways in colon cancer
por: Kim, Eui Joo, et al.
Publicado: (2018)

Swiprosin-1 Expression Is Up-Regulated through Protein Kinase C-θ and NF-κB Pathway in T Cells
por: Kim, Young-Dae, et al.
Publicado: (2013)

Tat-ATOX1 inhibits inflammatory responses via regulation of MAPK and NF-κB pathways
por: Kim, Dae Won, et al.
Publicado: (2018)

Vitamin C Activates Osteoblastogenesis and Inhibits Osteoclastogenesis via Wnt/β-Catenin/ATF4 Signaling Pathways
por: Choi, Hyeon Kyeong, et al.
Publicado: (2019)

Kurarinone promotes TRAIL-induced apoptosis by inhibiting NF-κB-dependent cFLIP expression in HeLa cells
por: Seo, Ok-Won, et al.
Publicado: (2012)

Anti-Inflammatory Effect of Meriania hexamera Sprague by Targeting Syk Kinase in NF-κB Signaling
por: Kwon, Ki Woong, et al.
Publicado: (2023)

Evolution of the Kdo(2)-lipid A biosynthesis in bacteria
por: Opiyo, Stephen O, et al.
Publicado: (2010)

Capric Acid Inhibits NO Production and STAT3 Activation during LPS-Induced Osteoclastogenesis
por: Park, Eun-Jung, et al.
Publicado: (2011)

Immuno-Stimulatory Activity of Escherichia coli Mutants Producing Kdo(2)-Monophosphoryl-Lipid A or Kdo(2)-Pentaacyl-Monophosphoryl-Lipid A
por: Wang, Biwen, et al.
Publicado: (2015)

Autophagy regulates trophoblast invasion by targeting NF-κB activity
por: Oh, Soo-young, et al.
Publicado: (2020)

Computational Insight Into the Structural Organization of Full-Length Toll-Like Receptor 4 Dimer in a Model Phospholipid Bilayer
por: Patra, Mahesh Chandra, et al.
Publicado: (2018)

Cytosolic Hsp60 Is Involved in the NF-κB-Dependent Survival of Cancer Cells via IKK Regulation
por: Chun, Jung Nyeo, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ugn70hidd40rlr5vt7agg2olgo