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Genetic and Functional Analysis of the DLG4 Gene Encoding the Post-Synaptic Density Protein 95 in Schizophrenia

Hypofunction of N-methyl-D-aspartate (NMDA) receptor-mediated signal transduction has been implicated in the pathophysiology of schizophrenia. Post-synaptic density protein 95 (PSD95) plays a critical role in regulating the trafficking and activity of the NMDA receptor and altered expression of the...

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Detalles Bibliográficos
Autores principales: Cheng, Min-Chih, Lu, Chao-Lin, Luu, Sy-Ueng, Tsai, Ho-Min, Hsu, Shih-Hsin, Chen, Tzu-Ting, Chen, Chia-Hsiang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996301/
https://www.ncbi.nlm.nih.gov/pubmed/21151988
http://dx.doi.org/10.1371/journal.pone.0015107