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A Unifying Framework for Evaluating the Predictive Power of Genetic Variants Based on the Level of Heritability Explained
An increasing number of genetic variants have been identified for many complex diseases. However, it is controversial whether risk prediction based on genomic profiles will be useful clinically. Appropriate statistical measures to evaluate the performance of genetic risk prediction models are requir...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996330/ https://www.ncbi.nlm.nih.gov/pubmed/21151957 http://dx.doi.org/10.1371/journal.pgen.1001230 |