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Role of Individual Subunits of the Neurospora crassa CSN Complex in Regulation of Deneddylation and Stability of Cullin Proteins

The Cop9 signalosome (CSN) is an evolutionarily conserved multifunctional complex that controls ubiquitin-dependent protein degradation in eukaryotes. We found seven CSN subunits in Neurospora crassa in a previous study, but only one subunit, CSN-2, was functionally characterized. In this study, we...

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Detalles Bibliográficos
Autores principales: Wang, Jiyong, Hu, Qiwen, Chen, Huijie, Zhou, Zhipeng, Li, Weihua, Wang, Ying, Li, Shaojie, He, Qun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996332/
https://www.ncbi.nlm.nih.gov/pubmed/21151958
http://dx.doi.org/10.1371/journal.pgen.1001232