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Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk

Human genome-wide association studies have linked single nucleotide polymorphisms (SNPs) on chromosome 9p21.3 near the INK4/ARF (CDKN2a/b) locus with susceptibility to atherosclerotic vascular disease (ASVD). Although this locus encodes three well-characterized tumor suppressors, p16(INK4a), p15(INK...

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Detalles Bibliográficos
Autores principales: Burd, Christin E., Jeck, William R., Liu, Yan, Sanoff, Hanna K., Wang, Zefeng, Sharpless, Norman E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996334/
https://www.ncbi.nlm.nih.gov/pubmed/21151960
http://dx.doi.org/10.1371/journal.pgen.1001233