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Designing coarse grained-and atom based-potentials for protein-protein docking
BACKGROUND: Protein-protein docking is a challenging computational problem in functional genomics, particularly when one or both proteins undergo conformational change(s) upon binding. The major challenge is to define a scoring function soft enough to tolerate these changes and specific enough to di...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996388/ https://www.ncbi.nlm.nih.gov/pubmed/21078143 http://dx.doi.org/10.1186/1472-6807-10-40 |