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Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse

BACKGROUND: Several active ingredients proposed as vaginal microbicides have been shown paradoxically to increase susceptibility to infection in mouse genital herpes (HSV-2) vaginal susceptibility models and in clinical trials. In addition, "inactive ingredients" (or excipients) used in to...

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Detalles Bibliográficos
Autores principales: Moench, Thomas R, Mumper, Russell J, Hoen, Timothy E, Sun, Mianmian, Cone, Richard A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996397/
https://www.ncbi.nlm.nih.gov/pubmed/21087496
http://dx.doi.org/10.1186/1471-2334-10-331