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Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse
BACKGROUND: Several active ingredients proposed as vaginal microbicides have been shown paradoxically to increase susceptibility to infection in mouse genital herpes (HSV-2) vaginal susceptibility models and in clinical trials. In addition, "inactive ingredients" (or excipients) used in to...
Autores principales: | Moench, Thomas R, Mumper, Russell J, Hoen, Timothy E, Sun, Mianmian, Cone, Richard A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996397/ https://www.ncbi.nlm.nih.gov/pubmed/21087496 http://dx.doi.org/10.1186/1471-2334-10-331 |
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