c- and N-myc Regulate Neural Precursor Cell Fate, Cell Cycle, and Metabolism to Direct Cerebellar Development

Separate murine knockout (KO) of either c- or N-myc genes in neural stem and precursor cells (NSC) driven by nestin-cre causes microcephaly. The cerebellum is particularly affected in the N-myc KO, leading to a strong reduction in cerebellar granule neural progenitors (CGNP) and mature granule neuro...

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Detalles Bibliográficos
Autores principales: Wey, Alice, Cerdeno, Veronica Martinez, Pleasure, David, Knoepfler, Paul S.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996535/
https://www.ncbi.nlm.nih.gov/pubmed/20658325
http://dx.doi.org/10.1007/s12311-010-0190-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996535/
https://www.ncbi.nlm.nih.gov/pubmed/20658325
http://dx.doi.org/10.1007/s12311-010-0190-9

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