Stable S/MAR-based episomal vectors are regulated at the chromatin level

Episomal vectors assembled from defined genetic components are a promising alternative to traditional gene therapy vectors that integrate in the host genome and may cause insertional mutations. The vector pEPI-eGFP is stably retained in the episomal state in cultured mammalian cells at low copy numb...

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Detalles Bibliográficos
Autores principales: Tessadori, Federico, Zeng, Kang, Manders, Erik, Riool, Martijn, Jackson, Dean, van Driel, Roel
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996544/
https://www.ncbi.nlm.nih.gov/pubmed/21080054
http://dx.doi.org/10.1007/s10577-010-9165-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996544/
https://www.ncbi.nlm.nih.gov/pubmed/21080054
http://dx.doi.org/10.1007/s10577-010-9165-4

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