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Stable S/MAR-based episomal vectors are regulated at the chromatin level

Episomal vectors assembled from defined genetic components are a promising alternative to traditional gene therapy vectors that integrate in the host genome and may cause insertional mutations. The vector pEPI-eGFP is stably retained in the episomal state in cultured mammalian cells at low copy numb...

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Detalles Bibliográficos
Autores principales:	Tessadori, Federico, Zeng, Kang, Manders, Erik, Riool, Martijn, Jackson, Dean, van Driel, Roel
Formato:	Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996544/ https://www.ncbi.nlm.nih.gov/pubmed/21080054 http://dx.doi.org/10.1007/s10577-010-9165-4

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