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A Single Amino Acid Substitution Changes Antigenicity of ORF2-Encoded Proteins of Hepatitis E Virus

Extensive genomic diversity has been observed among hepatitis E virus (HEV) strains. However, the implication of the genetic heterogeneity on HEV antigenic properties is uncertain. In this study, monoclonal antibodies (Mabs) against truncated ORF2-encoded proteins (aa452–617, designated p166 protein...

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Detalles Bibliográficos
Autores principales: Liang, Jiu-Hong, Dai, Xing, Dong, Chen, Meng, Ji-Hong
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996735/
https://www.ncbi.nlm.nih.gov/pubmed/21152284
http://dx.doi.org/10.3390/ijms11082962