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Rapid Synthesis of Flavor Compound 4-Ethyloctanoic Acid under Microwave Irradiation

Rapid synthesis of 4-ethyloctanoic acid by means of microwave irradiation is described. Diethyl malonate reacted with 2-ethyl-1-bromohexane in the presence of sodium ethoxide to give diethyl (2-ethylhexyl)malonate (1b). 1b was saponified in the solution of ethanol and potassium hydroxide and then ac...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Ping, Yin, De-Cai, Chen, Hai-Tao, Sun, Bao-Guo
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996780/
https://www.ncbi.nlm.nih.gov/pubmed/21152328
http://dx.doi.org/10.3390/ijms11104165