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Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells

Generation of mesencephalic dopamine (mesDA) neurons from human embryonic stem cells (hESCs) requires several stages of signaling from various extrinsic and intrinsic factors. To date, most methods incorporate exogenous treatment of Sonic hedgehog (SHH) to derive mesDA neurons. However, we and other...

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Detalles Bibliográficos
Autores principales: Denham, Mark, Thompson, Lachlan H, Leung, Jessie, Pébay, Alice, Björklund, Anders, Dottori, Mirella
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996857/
https://www.ncbi.nlm.nih.gov/pubmed/20799336
http://dx.doi.org/10.1002/stem.510