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Canonical Wnt/β-Catenin Regulation of Liver Receptor Homolog-1 Mediates Pluripotency Gene Expression

Delineating the signaling pathways that underlie ESC pluripotency is paramount for development of ESC applications in both the research and clinical settings. In culture pluripotency is maintained by leukemia inhibitory factor (LIF) stimulation of two separate signaling axes: Stat3/Klf4/Sox2 and PI3...

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Detalles Bibliográficos
Autores principales: Wagner, Ryan T, Xu, Xueping, Yi, Fei, Merrill, Bradley J, Cooney, Austin J
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996860/
https://www.ncbi.nlm.nih.gov/pubmed/20734354
http://dx.doi.org/10.1002/stem.502