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Mechanistic and functional versatility of radical SAM enzymes

Enzymes of the radical SAM (RS) superfamily catalyze a diverse assortment of reactions that proceed via intermediates containing unpaired electrons. The radical initiator is the common metabolite S-adenosyl-l-methionine (SAM), which is reductively cleaved to generate a 5′-deoxyadenosyl 5′-radical, a...

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Detalles Bibliográficos
Autores principales: Booker, Squire J, Grove, Tyler L
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996862/
https://www.ncbi.nlm.nih.gov/pubmed/21152342
http://dx.doi.org/10.3410/B2-52