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Voltage-dependent charge movement associated with activation of the CLC-5 2Cl(−)/1H(+) exchanger

The family of CLC proteins comprises both Cl(−) channels and Cl(−)/H(+) exchange transporters with varying degrees of voltage dependence. The human CLC-5 is an electrogenic voltage-dependent 2Cl(−)/1H(+) exchanger that gives rise to strongly outwardly rectifying currents when expressed. We conducted...

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Detalles Bibliográficos
Autores principales: Smith, Andrew J., Lippiat, Jonathan D.
Formato: Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996913/
https://www.ncbi.nlm.nih.gov/pubmed/20501796
http://dx.doi.org/10.1096/fj.09-150649