Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693

BACKGROUND: Inappropriate activation of AKT signaling is a relatively common occurrence in human tumors, and can be caused by activation of components of, or by loss or decreased activity of inhibitors of, this signaling pathway. A novel, pan AKT kinase inhibitor, GSK690693, was developed in order t...

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Detalles Bibliográficos
Autores principales: Kumar, Rakesh, Blakemore, Stephen J, Ellis, Catherine E, Petricoin, Emanuel F, Pratt, Dexter, Macoritto, Michael, Matthews, Andrea L, Loureiro, Joseph J, Elliston, Keith
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996947/
https://www.ncbi.nlm.nih.gov/pubmed/20604938
http://dx.doi.org/10.1186/1471-2164-11-419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996947/
https://www.ncbi.nlm.nih.gov/pubmed/20604938
http://dx.doi.org/10.1186/1471-2164-11-419

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