Copy number variation at leptin receptor gene locus associated with metabolic traits and the risk of type 2 diabetes mellitus

BACKGROUND: Recent efforts have been made to link complex human traits and disease susceptibility to DNA copy numbers. The leptin receptor (LEPR) has been implicated in obesity and diabetes. Mutations and genetic variations of LEPR gene have been discovered in rodents and humans. However, the associ...

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Detalles Bibliográficos
Autores principales: Jeon, Jae-Pil, Shim, Sung-Mi, Nam, Hye-Young, Ryu, Gil-Mi, Hong, Eun-Jung, Kim, Hyung-Lae, Han, Bok-Ghee
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996954/
https://www.ncbi.nlm.nih.gov/pubmed/20624279
http://dx.doi.org/10.1186/1471-2164-11-426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996954/
https://www.ncbi.nlm.nih.gov/pubmed/20624279
http://dx.doi.org/10.1186/1471-2164-11-426

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