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Copy number variation at leptin receptor gene locus associated with metabolic traits and the risk of type 2 diabetes mellitus
BACKGROUND: Recent efforts have been made to link complex human traits and disease susceptibility to DNA copy numbers. The leptin receptor (LEPR) has been implicated in obesity and diabetes. Mutations and genetic variations of LEPR gene have been discovered in rodents and humans. However, the associ...
Autores principales: | Jeon, Jae-Pil, Shim, Sung-Mi, Nam, Hye-Young, Ryu, Gil-Mi, Hong, Eun-Jung, Kim, Hyung-Lae, Han, Bok-Ghee |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996954/ https://www.ncbi.nlm.nih.gov/pubmed/20624279 http://dx.doi.org/10.1186/1471-2164-11-426 |
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