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Comparison of information-theoretic to statistical methods for gene-gene interactions in the presence of genetic heterogeneity

BACKGROUND: Multifactorial diseases such as cancer and cardiovascular diseases are caused by the complex interplay between genes and environment. The detection of these interactions remains challenging due to computational limitations. Information theoretic approaches use computationally efficient d...

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Detalles Bibliográficos
Autores principales: Sucheston, Lara, Chanda, Pritam, Zhang, Aidong, Tritchler, David, Ramanathan, Murali
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996983/
https://www.ncbi.nlm.nih.gov/pubmed/20815886
http://dx.doi.org/10.1186/1471-2164-11-487