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Comparison of information-theoretic to statistical methods for gene-gene interactions in the presence of genetic heterogeneity
BACKGROUND: Multifactorial diseases such as cancer and cardiovascular diseases are caused by the complex interplay between genes and environment. The detection of these interactions remains challenging due to computational limitations. Information theoretic approaches use computationally efficient d...
Autores principales: | Sucheston, Lara, Chanda, Pritam, Zhang, Aidong, Tritchler, David, Ramanathan, Murali |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996983/ https://www.ncbi.nlm.nih.gov/pubmed/20815886 http://dx.doi.org/10.1186/1471-2164-11-487 |
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