Natural selection retains overrepresented out-of-frame stop codons against frameshift peptides in prokaryotes

BACKGROUND: Out-of-frame stop codons (OSCs) occur naturally in coding sequences of all organisms, providing a mechanism of early termination of translation in incorrect reading frame so that the metabolic cost associated with frameshift events can be reduced. Given such a functional significance, we...

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Detalles Bibliográficos
Autores principales: Tse, Herman, Cai, James J, Tsoi, Hoi-Wah, Lam, Esther PT, Yuen, Kwok-Yung
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996987/
https://www.ncbi.nlm.nih.gov/pubmed/20828396
http://dx.doi.org/10.1186/1471-2164-11-491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996987/
https://www.ncbi.nlm.nih.gov/pubmed/20828396
http://dx.doi.org/10.1186/1471-2164-11-491

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