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Hif1α down-regulation is associated with transposition of great arteries in mice treated with a retinoic acid antagonist
BACKGROUND: Congenital heart defect (CHD) account for 25% of all human congenital abnormalities. However, very few CHD-causing genes have been identified so far. A promising approach for the identification of essential cardiac regulators whose mutations may be linked to human CHD, is the molecular a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996993/ https://www.ncbi.nlm.nih.gov/pubmed/20846364 http://dx.doi.org/10.1186/1471-2164-11-497 |