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Hif1α down-regulation is associated with transposition of great arteries in mice treated with a retinoic acid antagonist

BACKGROUND: Congenital heart defect (CHD) account for 25% of all human congenital abnormalities. However, very few CHD-causing genes have been identified so far. A promising approach for the identification of essential cardiac regulators whose mutations may be linked to human CHD, is the molecular a...

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Detalles Bibliográficos
Autores principales: Amati, Francesca, Diano, Laura, Campagnolo, Luisa, Vecchione, Lucia, Cipollone, Daria, Bueno, Susana, Prosperini, Gianluca, Desideri, Alessandro, Siracusa, Gregorio, Chillemi, Giovanni, Marino, Bruno, Novelli, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996993/
https://www.ncbi.nlm.nih.gov/pubmed/20846364
http://dx.doi.org/10.1186/1471-2164-11-497