Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom

BACKGROUND: The nutrient-sensing Tor pathway governs cell growth and is conserved in nearly all eukaryotic organisms from unicellular yeasts to multicellular organisms, including humans. Tor is the target of the immunosuppressive drug rapamycin, which in complex with the prolyl isomerase FKBP12 inhi...

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Detalles Bibliográficos
Autores principales: Shertz, Cecelia A, Bastidas, Robert J, Li, Wenjun, Heitman, Joseph, Cardenas, Maria E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997006/
https://www.ncbi.nlm.nih.gov/pubmed/20863387
http://dx.doi.org/10.1186/1471-2164-11-510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997006/
https://www.ncbi.nlm.nih.gov/pubmed/20863387
http://dx.doi.org/10.1186/1471-2164-11-510

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