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Nanoparticulate Transport of Oximes over an In Vitro Blood-Brain Barrier Model

BACKGROUND: Due to the use of organophosphates (OP) as pesticides and the availability of OP-type nerve agents, an effective medical treatment for OP poisonings is still a challenging problem. The acute toxicity of an OP poisoning is mainly due to the inhibition of acetylcholinesterase (AChE) in the...

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Detalles Bibliográficos
Autores principales: Wagner, Sylvia, Kufleitner, Jürgen, Zensi, Anja, Dadparvar, Miriam, Wien, Sascha, Bungert, Judith, Vogel, Tikva, Worek, Franz, Kreuter, Jörg, von Briesen, Hagen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997055/
https://www.ncbi.nlm.nih.gov/pubmed/21151975
http://dx.doi.org/10.1371/journal.pone.0014213