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Concerted Regulation of cGMP and cAMP Phosphodiesterases in Early Cardiac Hypertrophy Induced by Angiotensin II

Left ventricular hypertrophy leads to heart failure and represents a high risk leading to premature death. Cyclic nucleotides (cAMP and cGMP) play a major role in heart contractility and cyclic nucleotide phosphodiesterases (PDEs) are involved in different stages of advanced cardiac diseases. We hav...

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Detalles Bibliográficos
Autores principales: Mokni, Walid, Keravis, Thérèse, Etienne-Selloum, Nelly, Walter, Alison, Kane, Modou O., Schini-Kerth, Valérie B., Lugnier, Claire
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997062/
https://www.ncbi.nlm.nih.gov/pubmed/21151982
http://dx.doi.org/10.1371/journal.pone.0014227