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Analysis of Kinase Gene Expression Patterns across 5681 Human Tissue Samples Reveals Functional Genomic Taxonomy of the Kinome

Kinases play key roles in cell signaling and represent major targets for drug development, but the regulation of their activation and their associations with health and disease have not been systematically analyzed. Here, we carried out a bioinformatic analysis of the expression levels of 459 human...

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Detalles Bibliográficos
Autores principales: Kilpinen, Sami, Ojala, Kalle, Kallioniemi, Olli
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997066/
https://www.ncbi.nlm.nih.gov/pubmed/21151926
http://dx.doi.org/10.1371/journal.pone.0015068