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Decreased Level of Nurr1 in Heterozygous Young Adult Mice Leads to Exacerbated Acute and Long-Term Toxicity after Repeated Methamphetamine Exposure

The abuse of psychostimulants, such as methamphetamine (METH), is prevalent in young adults and could lead to long-term adaptations in the midbrain dopamine system in abstinent human METH abusers. Nurr1 is a gene that is critical for the survival and maintenance of dopaminergic neurons and has been...

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Detalles Bibliográficos
Autores principales: Luo, Yu, Wang, Yun, Kuang, Serena Y., Chiang, Yung-Hsiao, Hoffer, Barry
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997078/
https://www.ncbi.nlm.nih.gov/pubmed/21151937
http://dx.doi.org/10.1371/journal.pone.0015193