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Deficiency of Vasodilator-Stimulated Phosphoprotein (VASP) Increases Blood-Brain-Barrier Damage and Edema Formation after Ischemic Stroke in Mice

BACKGROUND: Stroke-induced brain edema formation is a frequent cause of secondary infarct growth and deterioration of neurological function. The molecular mechanisms underlying edema formation after stroke are largely unknown. Vasodilator-stimulated phosphoprotein (VASP) is an important regulator of...

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Detalles Bibliográficos
Autores principales: Kraft, Peter, Benz, Peter Michael, Austinat, Madeleine, Brede, Marc Elmar, Schuh, Kai, Walter, Ulrich, Stoll, Guido, Kleinschnitz, Christoph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997079/
https://www.ncbi.nlm.nih.gov/pubmed/21151938
http://dx.doi.org/10.1371/journal.pone.0015106