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Development and Function of CD94-Deficient Natural Killer Cells

The CD94 transmembrane-anchored glycoprotein forms disulfide-bonded heterodimers with the NKG2A subunit to form an inhibitory receptor or with the NKG2C or NKG2E subunits to assemble a receptor complex with activating DAP12 signaling proteins. CD94 receptors expressed on human and mouse NK cells and...

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Detalles Bibliográficos
Autores principales: Orr, Mark T., Wu, Jun, Fang, Min, Sigal, Luis J., Spee, Pieter, Egebjerg, Thomas, Dissen, Erik, Fossum, Sigbjørn, Phillips, Joseph H., Lanier, Lewis L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997080/
https://www.ncbi.nlm.nih.gov/pubmed/21151939
http://dx.doi.org/10.1371/journal.pone.0015184