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Influence of hepatic impairment on pharmacokinetics of the human GLP-1 analogue, liraglutide
AIMS: To compare the pharmacokinetics (PK) of a single-dose of liraglutide in subjects with hepatic impairment. METHODS: This parallel group, open label trial involved four groups of six subjects with healthy, mild, moderate and severe hepatic impairment, respectively. Each subject received 0.75 mg...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Science Inc
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997321/ https://www.ncbi.nlm.nih.gov/pubmed/21175436 http://dx.doi.org/10.1111/j.1365-2125.2010.03762.x |