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Influence of hepatic impairment on pharmacokinetics of the human GLP-1 analogue, liraglutide

AIMS: To compare the pharmacokinetics (PK) of a single-dose of liraglutide in subjects with hepatic impairment. METHODS: This parallel group, open label trial involved four groups of six subjects with healthy, mild, moderate and severe hepatic impairment, respectively. Each subject received 0.75 mg...

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Detalles Bibliográficos
Autores principales:	Flint, Anne, Nazzal, Khalil, Jagielski, Pawel, Hindsberger, Charlotte, Zdravkovic, Milan
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Science Inc 2010
Materias:	Pharmacokinetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997321/ https://www.ncbi.nlm.nih.gov/pubmed/21175436 http://dx.doi.org/10.1111/j.1365-2125.2010.03762.x

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