Granulocyte-colony stimulating factor drives the in vitro differentiation of human dendritic cells that induce anergy in naïve T cells

G-CSF is a modulator of T-cell and DC functions. Previous reports show that monocytes from G-CSF-treated (post-G) healthy donors differentiate into tolerogenic DC in vitro in the presence of autologous serum, containing high levels of IL-10 and IFN-α, and in turn induce type 1 Treg (Tr1) cells. Howe...

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Detalles Bibliográficos
Autores principales: Rossetti, Maura, Gregori, Silvia, Roncarolo, Maria Grazia
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997328/
https://www.ncbi.nlm.nih.gov/pubmed/20957751
http://dx.doi.org/10.1002/eji.201040659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997328/
https://www.ncbi.nlm.nih.gov/pubmed/20957751
http://dx.doi.org/10.1002/eji.201040659

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