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Cationic nano-copolymers mediated IKKβ targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery

PURPOSE: To investigate the efficacy and safety of cationic nano-copolymers CS-g-(PEI-b-mPEG) mediated IκB kinase beta (IKKβ) targeting siRNA in modulating wound healing in a monkey model of glaucoma filtration surgery. METHODS: The IKKβ targeting siRNAs were chemically synthesized and screened in c...

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Detalles Bibliográficos
Autores principales: Ye, Hehua, Qian, Yiyong, Lin, Mingkai, Duan, Yongheng, Sun, Xuerong, Zhuo, Yehong, Ge, Jian
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997334/
https://www.ncbi.nlm.nih.gov/pubmed/21139997