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Acetazolamide-based fungal chitinase inhibitors
Chitin is an essential structural component of the fungal cell wall. Chitinases are thought to be important for fungal cell wall remodelling, and inhibition of these enzymes has been proposed as a potential strategy for development of novel anti-fungals. The fungal pathogen Aspergillus fumigatus pos...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997425/ https://www.ncbi.nlm.nih.gov/pubmed/21044846 http://dx.doi.org/10.1016/j.bmc.2010.09.062 |