Cargando…
Acetazolamide-based fungal chitinase inhibitors
Chitin is an essential structural component of the fungal cell wall. Chitinases are thought to be important for fungal cell wall remodelling, and inhibition of these enzymes has been proposed as a potential strategy for development of novel anti-fungals. The fungal pathogen Aspergillus fumigatus pos...
Autores principales: | Schüttelkopf, Alexander W., Gros, Ludovic, Blair, David E., Frearson, Julie A., van Aalten, Daan M.F., Gilbert, Ian H. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997425/ https://www.ncbi.nlm.nih.gov/pubmed/21044846 http://dx.doi.org/10.1016/j.bmc.2010.09.062 |
Ejemplares similares
-
Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors
por: Lockhart, Deborah E.A., et al.
Publicado: (2014) -
Structure-Based Dissection of the Natural Product Cyclopentapeptide Chitinase Inhibitor Argifin
por: Andersen, Ole A., et al.
Publicado: (2008) -
Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope
por: Lamb, Daniel, et al.
Publicado: (2008) -
Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold
por: Dixon, Mark J., et al.
Publicado: (2009) -
Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis
por: Striebeck, Alexander, et al.
Publicado: (2013)