Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation

When a replicative DNA polymerase stalls upon encountering a lesion on the template strand, it is relieved by other low-processivity polymerase(s), which insert nucleotide(s) opposite the lesion, extend by a few nucleotides, and dissociate from the 3′-OH. The replicative polymerase then resumes DNA...

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Detalles Bibliográficos
Autores principales: Takezawa, Jun, Ishimi, Yukio, Aiba, Naomi, Yamada, Kouichi
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997509/
https://www.ncbi.nlm.nih.gov/pubmed/21151666
http://dx.doi.org/10.4061/2010/750296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997509/
https://www.ncbi.nlm.nih.gov/pubmed/21151666
http://dx.doi.org/10.4061/2010/750296

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