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A New Framework for Studying the Isochore Evolution: Estimation of the Equilibrium GC Content Based on the Temporal Mutation Rate Model

Isochore is the genome-wide mosaic structure in guanine-cytosine (GC) content. The origin of isochores is thought to have emerged in the ancestral amniote genome, and the GC-rich isochore is eroded in the mammalian lineages. However, there are many enigmas in the isochore evolution: 1) although all...

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Detalles Bibliográficos
Autores principales: OOta, Satoshi, Kawamura, Kazuhiro, Kawai, Yosuke, Saitou, Naruya
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997559/
https://www.ncbi.nlm.nih.gov/pubmed/20675617
http://dx.doi.org/10.1093/gbe/evq041