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Assigning Significance in Label-Free Quantitative Proteomics to Include Single-Peptide-Hit Proteins with Low Replicates
When sample replicates are limited in a label-free proteomics experiment, selecting differentially regulated proteins with an assignment of statistical significance remains difficult for proteins with a single-peptide hit or a small fold-change. This paper aims to address this issue. An important co...
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| Formato: | Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997754/ https://www.ncbi.nlm.nih.gov/pubmed/21152383 http://dx.doi.org/10.1155/2010/731582 |