Activation of Protein Serine/Threonine Phosphatase PP2Cα Efficiently Prevents Liver Fibrosis

BACKGROUND: Over-activation of TGFβ signaling pathway and uncontrolled cell proliferation of hepatic stellate cells (HSCs) play pivotal roles in liver fibrogenesis, while the protein serine/threonine phosphatase PP2Cα was reported to negatively regulate TGFβ signaling pathway and cell cycle. Our stu...

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Detalles Bibliográficos
Autores principales: Wang, Lirui, Wang, Xu, Chen, Jing, Yang, Zhengyi, Yu, Liang, Hu, Lihong, Shen, Xu
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997772/
https://www.ncbi.nlm.nih.gov/pubmed/21151953
http://dx.doi.org/10.1371/journal.pone.0014230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997772/
https://www.ncbi.nlm.nih.gov/pubmed/21151953
http://dx.doi.org/10.1371/journal.pone.0014230

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