LMNA E82K Mutation Activates FAS and Mitochondrial Pathways of Apoptosis in Heart Tissue Specific Transgenic Mice

The lamin A/C (LMNA), nuclear intermediate filament proteins, is a basic component of the nuclear lamina. Mutations in LMNA are associated with a broad range of laminopathies, congenital diseases affecting tissue regeneration and homeostasis. Heart tissue specific transgenic mice of human LMNA E82K,...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Dan, Lian, Hong, Zhang, Xiaojuan, Shao, Haitao, Huang, Lan, Qin, Chuan, Zhang, Lianfeng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997782/
https://www.ncbi.nlm.nih.gov/pubmed/21151901
http://dx.doi.org/10.1371/journal.pone.0015167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997782/
https://www.ncbi.nlm.nih.gov/pubmed/21151901
http://dx.doi.org/10.1371/journal.pone.0015167

Ejemplares similares