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LMNA E82K Mutation Activates FAS and Mitochondrial Pathways of Apoptosis in Heart Tissue Specific Transgenic Mice

The lamin A/C (LMNA), nuclear intermediate filament proteins, is a basic component of the nuclear lamina. Mutations in LMNA are associated with a broad range of laminopathies, congenital diseases affecting tissue regeneration and homeostasis. Heart tissue specific transgenic mice of human LMNA E82K,...

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Detalles Bibliográficos
Autores principales:	Lu, Dan, Lian, Hong, Zhang, Xiaojuan, Shao, Haitao, Huang, Lan, Qin, Chuan, Zhang, Lianfeng
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997782/ https://www.ncbi.nlm.nih.gov/pubmed/21151901 http://dx.doi.org/10.1371/journal.pone.0015167

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