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The role of fibroblast Tiam1 in tumor cell invasion and metastasis

The co-evolution of tumors and their microenvironment involves bidirectional communication between tumor cells and tumor-associated stroma. Various cell types are present in tumor-associated stroma, of which fibroblasts are the most abundant. The Rac exchange factor Tiam1 is implicated in multiple s...

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Detalles Bibliográficos
Autores principales: Xu, Kun, Rajagopal, Soumitra, Klebba, Ina, Dong, Shumin, Ji, Yuxin, Liu, Jiewei, Kuperwasser, Charlotte, Garlick, Jonathan A., Naber, Stephen P., Buchsbaum, Rachel J.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997941/
https://www.ncbi.nlm.nih.gov/pubmed/20802514
http://dx.doi.org/10.1038/onc.2010.385