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The role of fibroblast Tiam1 in tumor cell invasion and metastasis
The co-evolution of tumors and their microenvironment involves bidirectional communication between tumor cells and tumor-associated stroma. Various cell types are present in tumor-associated stroma, of which fibroblasts are the most abundant. The Rac exchange factor Tiam1 is implicated in multiple s...
Autores principales: | Xu, Kun, Rajagopal, Soumitra, Klebba, Ina, Dong, Shumin, Ji, Yuxin, Liu, Jiewei, Kuperwasser, Charlotte, Garlick, Jonathan A., Naber, Stephen P., Buchsbaum, Rachel J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997941/ https://www.ncbi.nlm.nih.gov/pubmed/20802514 http://dx.doi.org/10.1038/onc.2010.385 |
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